●Berberine yog dab tsi?
Berberine yog lub ntuj alkaloid muab rho tawm los ntawm cov hauv paus hniav, stems thiab barks ntawm ntau yam nroj tsuag, xws li Coptis chinensis, Phellodendron amurense thiab Berberis vulgaris. Nws yog lub ntsiab active ingredient ntawm Coptis chinensis rau antibacterial nyhuv.
Berberine yog lub ntsej muag daj-zoo li siv lead ua nrog lub iab saj. Cov khoom xyaw tseem ceeb hauv Coptis chinensis yog berberine hydrochloride. Qhov no yog ib qho isoquinoline alkaloid faib nyob rau hauv ntau yam tshuaj ntsuab. Nws muaj nyob rau hauv Coptis chinensis nyob rau hauv daim ntawv ntawm hydrochloride (berberine hydrochloride). Cov kev tshawb fawb tau pom tias cov tshuaj no tuaj yeem siv los kho cov qog nqaij hlav, kab mob siab, kab mob plawv, ntshav siab, o, kab mob thiab kab mob, raws plab, Alzheimer's kab mob thiab mob caj dab.
● Cov txiaj ntsig kev noj qab haus huv ntawm Berberine yog dab tsi?
1.Antioxidant
Raws li ib txwm muaj, tib neeg lub cev tswj hwm qhov sib npaug ntawm antioxidants thiab prooxidants. Oxidative stress yog cov txheej txheem tsim kev puas tsuaj uas tej zaum yuav yog ib qho tseem ceeb ntawm tus neeg nruab nrab ntawm kev puas tsuaj ntawm cov qauv ntawm tes, yog li ua rau muaj ntau yam kab mob xws li kab mob plawv, mob qog noj ntshav, mob qog noj ntshav thiab ntshav qab zib. Kev tsim cov pa oxygen ntau dhau (ROS), feem ntau dhau los ntawm kev txhawb nqa ntau dhau ntawm NADPH los ntawm cytokines lossis los ntawm mitochondrial electron thauj saw thiab xanthine oxidase, tuaj yeem ua rau oxidative kev nyuaj siab. Kev sim tau pom tias berberine metabolites thiab berberine qhia tau zoo heev -OH scavenging kev ua si, uas yog kwv yees sib npaug rau cov muaj zog antioxidant vitamin C. Kev tswj hwm ntawm berberine rau cov nas mob ntshav qab zib tuaj yeem soj ntsuam qhov nce hauv SOD (superoxide dismutase) kev ua thiab txo qis hauv MDA (a Cov cim ntawm lipid peroxidation) qib [1]. Cov txiaj ntsig ntxiv qhia tau hais tias qhov kev ua si ntawm berberine muaj feem cuam tshuam nrog nws txoj haujlwm ferrous ion chelating, thiab C-9 hydroxyl pawg ntawm berberine yog qhov tseem ceeb.
2.Anti-mob
Muaj ntau cov lus ceeb toom txog kev tiv thaiv mob qog noj ntshav ntawmua berberine. Ntau yam kev tshawb fawb hauv xyoo tas los no tau pom tias berberine yog qhov tseem ceeb hauv kev kho mob qog noj ntshav loj xws li mob qog noj ntshav ntawm zes qe menyuam, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob ntsws cancer, mob qog noj ntshav, mob qog noj ntshav, mob raum, mob qog noj ntshav, thiab mob qog nqaij hlav prostate. [2]. Berberine tuaj yeem cuam tshuam kev loj hlob ntawm cov qog hlwb los ntawm kev cuam tshuam nrog ntau lub hom phiaj thiab cov txheej txheem. Nws tuaj yeem hloov qhov kev qhia ntawm oncogenes thiab carcinogenesis ntsig txog cov noob kom ua tiav lub hom phiaj ntawm kev tswj hwm cov haujlwm ntawm cov enzymes cuam tshuam los tiv thaiv kev loj hlob.
3.Lowering ntshav lipids thiab tiv thaiv kab mob plawv
Berberine plays lub luag haujlwm tseem ceeb hauv kev kho cov kab mob plawv thiab muaj ntau yam kev siv. Berberine ua tiav lub hom phiaj ntawm kev tiv thaiv arrhythmia los ntawm kev txo qhov tshwm sim ntawm ventricular premature beats thiab inhibiting qhov tshwm sim ntawm ventricular tachycardia. Qhov thib ob, dyslipidemia yog ib qho tseem ceeb ntawm kev pheej hmoo rau cov kab mob plawv, tus cwj pwm los ntawm kev nce qib ntawm tag nrho cov roj (cholesterol), triglycerides, thiab qis-density lipoprotein cholesterol (LDL), thiab txo qis ntawm high-density lipoprotein (HDL), thiab berberine muaj peev xwm tswj tau cov roj lipoprotein tsawg. stability ntawm cov ntsuas no. Lub sijhawm ntev hyperlipidemia yog ib qho tseem ceeb ntawm kev tsim cov atherosclerotic plaque. Nws tau tshaj tawm tias berberine cuam tshuam rau LDL receptors hauv hepatocytes kom txo qis tib neeg cov roj cholesterol hauv hepatocytes. Tsis tas li ntawd xwb,ua berberinemuaj cov nyhuv inotropic zoo thiab tau siv los kho lub plawv tsis ua haujlwm.
4.Lows ntshav qab zib thiab tswj endocrine
Mob ntshav qab zib mellitus (DM) yog ib qho teeb meem metabolic uas tshwm sim los ntawm cov ntshav qab zib siab (hyperglycemia) tshwm sim los ntawm qhov tsis muaj peev xwm ntawm pancreatic B hlwb los tsim cov tshuaj insulin txaus, lossis poob ntawm cov ntaub so ntswg zoo teb rau insulin. Cov nyhuv hypoglycemic ntawm berberine tau pom tshwm sim nyob rau xyoo 1980s hauv kev kho cov neeg mob ntshav qab zib raws plab.
Ntau qhov kev tshawb fawb tau pom tiasua berberinetxo cov ntshav qab zib los ntawm cov txheej txheem hauv qab no:
● inhibits mitochondrial qabzib oxidation thiab nkoos glycolysis, tom qab ua kom qabzib metabolism;
● Txo cov qib ATP los ntawm inhibiting mitochondrial muaj nuj nqi hauv daim siab;
● inhibits qhov kev ua ntawm DPP 4 (ib tug ubiquitous serine protease), yog li cleaving tej peptides uas ua rau kom cov insulin nce nyob rau hauv lub xub ntiag ntawm hyperglycemia.
● Berberine muaj txiaj ntsig zoo rau kev txhim kho cov tshuaj insulin thiab kev siv cov piam thaj hauv cov ntaub so ntswg los ntawm kev txo cov lipids (tshwj xeeb tshaj yog triglycerides) thiab plasma dawb fatty acid qib.
Cov ntsiab lus
Niaj hnub no,ua berberinetuaj yeem tsim cov khoom tsim thiab hloov kho los ntawm cov txheej txheem siv lead ua engineering. Nws muaj tus nqi qis thiab kev siv tshuab siab heev. Nrog rau kev txhim kho kev tshawb fawb txog kev kho mob thiab kev sib sib zog nqus ntawm kev tshawb fawb tshuaj, berberine yuav muaj tseeb qhia cov tshuaj muaj txiaj ntsig ntau dua. Ntawm qhov tod tes, berberine tsis tau tsuas yog ua tiav cov txiaj ntsig zoo kawg nkaus hauv kev tshawb fawb tshuaj tshuaj hauv tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, tiv thaiv qog, tiv thaiv ntshav qab zib, thiab kho cov kab mob plawv thiab cerebrovascular, tab sis kuj nws cov qauv siv lead ua engineering thiab morphological tsom xam. tau txais kev saib xyuas dav dav. Vim nws cov txiaj ntsig tseem ceeb thiab tsis muaj tshuaj lom thiab cov kev mob tshwm sim, nws muaj peev xwm zoo hauv kev siv tshuaj kho mob thiab muaj kev cia siab dav. Nrog rau txoj kev loj hlob ntawm cell biology, lub pharmacological mechanism ntawm berberine yuav qhia meej los ntawm cov cellular theem thiab txawm lub molecular thiab lub hom phiaj theem, muab ntau theoretical hauv paus rau nws cov kev kho mob daim ntawv thov.
● NEWGREEN SupplyBerberine/Liposomal Berberine Powder / Capsules / ntsiav tshuaj
Post lub sij hawm: Oct-28-2024
