Dab tsi yogGlabridin?
Glabridin yog ib qho flavonoid rho tawm los ntawm cov hauv paus hniav ntawm licorice (Glycyrrhiza glabra) thiab muaj ntau yam kev ua ub no thiab kev noj qab haus huv. glabridin yog lub npe hu rau nws cov haib whitening, antioxidant thiab anti-inflammatory zog thiab yog dav siv nyob rau hauv kev tu tawv nqaij thiab tshuaj pleev ib ce.
Glycyrrhiza glabra L. yog ib tsob nroj muaj xyoob ntoo uas loj hlob nyob rau sab qab teb Europe, Asia, thiab thaj av Mediterranean. Nws yog cog nyob rau hauv Russia, Spain, Iran, thiab Is Nrias teb. Cov nroj tsuag ntawm G. glabra yog li 1-1.5 meters siab, nrog me me tsaus ntsuab nplooj, daj, xiav, thiab violet paj, thiab ib tug qab zib rhizome.
Glabridin yog ib qho tseem ceeb ntawm flavonoids hauv Glycyrrhiza glabra. Nws qhia tau hais tias muaj zog tiv thaiv dawb radical oxidation nyhuv hauv cytochrome P450 / NADPH oxidation system, thiab tuaj yeem cuam tshuam cov dawb radicals uas tsim thaum lub sij hawm metabolism hauv lub cev los tiv thaiv oxidation-sensitive biomacromolecules (tsawg-density lipoprotein LDL, DNA) thiab cell phab ntsa los ntawm kev puas tsuaj los ntawm dawb radical oxidation. Qhov no tuaj yeem tiv thaiv thiab kho qee yam kev hloov pauv pathological cuam tshuam nrog dawb radical oxidation, xws li atherosclerosis thiab cell aging. Tsis tas li ntawd, glabridin muaj qee yam cuam tshuam los txo cov ntshav lipids thiab ntshav siab. Cov kev tshawb fawb Italian kuj tau lees paub tias Glabridin muaj cov nyhuv ua kom qab los noj mov, uas tuaj yeem txo cov rog yam tsis muaj qhov hnyav. Tom qab rov kuaj dua, cov teebmeem tseem ceeb yog raws li nram no: 1. Whitening, inhibiting melanin; 2. Anti-inflammatory nyhuv; 3. Antioxidant nyhuv; 4. Tshuaj tua kab mob.
Physical And Chemical Properties ofGlabridin
1. Chemical Structure
Lub npe tshuaj: Glabridin
Cov roj formula: C20H20O4
Molecular Luj: 324.37 g / mol
Cov yam ntxwv ntawm tus yam ntxwv: Glabridin yog ib qho flavonoid compound nrog cov qauv flavonoid caj qaum. Nws muaj ob lub nplhaib uas muaj ntxhiab (A thiab B) txuas los ntawm tus choj peb-carbon uas ua rau lub nplhaib kaw.
2. Lub cev muaj zog
Cov tsos mob: Glabridin feem ntau tshwm li cov hmoov dawb lossis daj daj crystalline hmoov.
Solubility:
Dej: Tsis zoo soluble hauv dej.
Organic Solvents: Soluble hauv cov kuab tshuaj organic xws li ethanol, methanol, thiab propylene glycol.
Melting Point: Kwv yees li 156-158 ° C (313-316 ° F).
Cov ntxhiab tsw: Glabridin feem ntau tsis muaj ntxhiab tsw txawv.
3. Cov khoom siv tshuaj
Stability: Glabridin kuj ruaj khov nyob rau hauv ib txwm muaj tab sis tuaj yeem degrade thaum raug lub teeb, kub, lossis acidic. Nws raug nquahu kom khaws cia rau hauv qhov chaw txias, qhuav, deb ntawm tshav ntuj ncaj qha.
pH rhiab heev: Glabridin rhiab heev rau pH hloov thiab tej zaum yuav degrade nyob rau hauv high acidic los yog yooj yim ib puag ncig.
Reactivity: Raws li ib tug flavonoid, glabridin tuaj yeem raug cov tshuaj lom neeg muaj feem xyuam nrog phenolic tebchaw, xws li oxidation thiab conjugation.
Dab tsi yog Cov txiaj ntsig ntawmGlabridin?
1. Daim tawv nqaij dawb thiab ci ntsa iab
- Inhibition ntawm Tyrosinase: Glabridin paub zoo rau nws cov tawv nqaij dawb. Nws inhibits qhov kev ua ntawm tyrosinase, ib qho enzyme tseem ceeb rau melanin ntau lawm, yog li txo qhov tsim ntawm qhov chaw tsaus thiab hyperpigmentation.
- Txawm tias tawv nqaij: Los ntawm kev txo melanin synthesis, glabridin pab kom ua tiav cov tawv nqaij ntau dua thiab ci dua.
2. Antioxidant Properties
- Dawb Radical Scavenging: Glabridin muaj zog antioxidant zog, uas pab nyob rau hauv neutralizing dawb radicals. Qhov no txo oxidative kev nyuaj siab thiab tiv thaiv cellular puas.
- Kev Tiv Thaiv Kev Laus: Cov haujlwm antioxidant ntawm glabridin pab txo qis cov cim ntawm kev laus, xws li cov kab zoo, wrinkles, thiab hnub nyoog me me, los ntawm kev tiv thaiv daim tawv nqaij los ntawm kev puas tsuaj oxidative.
3. Anti-Inflammatory Effects
- Txo qhov mob: Glabridin nthuav tawm cov khoom tiv thaiv kab mob, uas pab txo cov tawv nqaij o, liab, thiab o.
- Soothing Effect: Nws tuaj yeem soothe tawv nqaij thiab muaj txiaj ntsig zoo rau cov mob xws li pob txuv, eczema, thiab rosacea
4. Kev tiv thaiv kab mob
- Inhibition of Pathogens: Glabridin tau ua kom pom cov tshuaj tiv thaiv kab mob tiv thaiv ntau yam kab mob thiab fungi. Qhov no ua rau nws muaj txiaj ntsig zoo hauv kev tiv thaiv thiab kho cov kab mob ntawm daim tawv nqaij.
- Kev kho pob txuv: Nws cov tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob ua rau glabridin zoo hauv kev kho pob txuv los ntawm kev txo cov kab mob loj hlob thiab mob.
5. Kev tiv thaiv UV
- Photoprotection: Glabridin tuaj yeem muab qee theem ntawm kev tiv thaiv UV hluav taws xob. Nws pab txo qis UV-vim cov tawv nqaij puas, xws li tshav kub hnyiab thiab photoaging.
- Synergistic Effect: Thaum siv ua ke nrog lwm cov tshuaj pleev thaiv hnub, glabridin tuaj yeem txhim kho cov nyhuv photoprotective tag nrho.
6. Kev Kho Mob
- Txhawb Kev Kho Mob: Glabridin tuaj yeem txhawb kev kho qhov txhab los ntawm kev txo qhov mob thiab oxidative kev nyuaj siab, thiab los ntawm kev txhawb kev tsim kho ntawm daim tawv nqaij.
- Kev txo qis: Nws kuj tseem tuaj yeem pab txo qis cov nti los ntawm kev txhawb nqa kev noj qab haus huv ntawm daim tawv nqaij.
7. Kev tu plaub hau
- Scalp Health: Glabridin's anti-inflammatory thiab antimicrobial zog tuaj yeem pab cov tawv nqaij noj qab haus huv, txo cov dandruff thiab tawv taub hau khaus.
- Cov plaub hau loj hlob: Los ntawm kev txhim kho tawv taub hau kev noj qab haus huv, glabridin kuj tseem tuaj yeem txhawb cov plaub hau kev loj hlob.
Dab tsi yog Cov Ntawv Thov NtawmGlabridin?
Tshuaj pleev ib ce thiab Skincare
1. Cov khoom siv tawv nqaij dawb
- Whitening Creams thiab Serums: Glabridin yog ib qho tseem ceeb muaj nyob rau hauv ntau daim tawv nqaij dawb thiab ci khoom vim nws muaj peev xwm inhibit tyrosinase kev ua si thiab txo melanin ntau lawm.
- Spot Treatments: Siv nyob rau hauv cov formulations tsom txo qhov tsaus me ntsis, hyperpigmentation, thiab cov tawv nqaij tsis sib xws.
2.Anti-aging khoom
- Anti-aging Creams thiab Lotions: Cov khoom antioxidant ntawm glabridin pab txo cov cim ntawm kev laus, xws li cov kab zoo, wrinkles, thiab hnub nyoog me ntsis.
- Eye Creams: Feem ntau suav nrog hauv cov tshuaj pleev qhov muag kom txo tau cov voj voog tsaus thiab puffiness.
3.Anti-Inflammatory thiab Soothing khoom
- Soothing Gels thiab Creams: Glabridin's anti-inflammatory zog ua rau nws haum rau cov khoom tsim los soothe khaus khaus lossis khaus tawv nqaij.
- Kho pob txuv: Siv cov khoom kho pob txuv kom txo tau qhov mob thiab kab mob loj hlob.
4. Cov khoom siv tiv thaiv tshav ntuj
- Cov tshuaj tiv thaiv tshav ntuj: Glabridin tuaj yeem suav nrog hauv cov tshuaj pleev thaiv hnub los muab kev tiv thaiv ntxiv tiv thaiv UV-induced tawv nqaij puas.
- After-Sun Care: Siv nyob rau hauv cov khoom tom qab tshav ntuj los soothe thiab kho cov tawv nqaij sunburned.
Pharmaceuticals
1. Tshuaj kho mob
- Anti-Inflammatory Creams: Siv cov tshuaj pleev ib ce los kho cov tawv nqaij mob xws li eczema, psoriasis, thiab dermatitis.
- Cov Tshuaj Hniav Kho Mob: Muaj nyob rau hauv cov qauv tsim los txhawb kev kho qhov txhab thiab txo cov caws pliav.
2. Qhov ncauj ntxiv
- Antioxidant Ntxiv: Glabridin's antioxidant zog ua rau nws muaj txiaj ntsig zoo hauv cov tshuaj hauv qhov ncauj txhawm rau txo oxidative kev nyuaj siab thiab txhawb kev noj qab haus huv tag nrho.
- Immune Boosters: Siv nyob rau hauv cov tshuaj uas tsim los txhim kho kev tiv thaiv kab mob vim nws cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob.
Kev tu plaub hau
1. Kev kho tawv taub hau
- Anti-Dandruff Shampoos: Glabridin's antimicrobial thiab anti-inflammatory zog ua rau nws muaj txiaj ntsig zoo hauv kev kho dandruff thiab tawv taub hau khaus.
- Scalp Serums: Siv nyob rau hauv cov tawv taub hau serums los txhawb lub taub hau noj qab haus huv ib puag ncig thiab muaj peev xwm txhawb cov plaub hau kev loj hlob.
2. Cov tshuaj kho plaub hau
- Cov Tshuaj Kho Hniav thiab Cov Hniav Plaub Hau: Muaj nyob rau hauv cov khoom tu plaub hau los muab kev tiv thaiv antioxidant thiab txhim kho plaub hau kev noj qab haus huv.
Khoom noj khoom haus thiab dej haus
Khoom noj khoom haus
- Kev Noj Qab Haus Huv: Glabridin tuaj yeem ntxiv rau cov dej qab zib noj qab haus huv thiab dej haus ua haujlwm kom muab cov txiaj ntsig antioxidant thiab tiv thaiv kab mob.
- Cov Khoom Noj Khoom Haus: Siv rau hauv cov khoom noj khoom haus thiab khoom noj txom ncauj los txhawb kev noj qab haus huv thiab kev noj qab haus huv.
Kev tshawb fawb thiab kev loj hlob
Kev tshawb fawb biomedical
- Kev Tshawb Fawb Txog Kab Mob: Glabridin tau kawm txog nws cov peev xwm tiv thaiv kab mob qog noj ntshav, suav nrog nws lub peev xwm los tiv thaiv qog nqaij hlav qog noj ntshav thiab ua rau apoptosis.
- Kev Tshawb Fawb Txog Kab Mob: Tshawb xyuas rau nws cov txiaj ntsig zoo hauv kev tswj cov kab mob ntev xws li ntshav qab zib thiab kab mob plawv vim nws cov tshuaj tiv thaiv kab mob thiab antioxidant.
Cov lus nug ntsig txog koj tuaj yeem txaus siab rau:
Nws siv sijhawm ntev npaum li cas rau licorice extractglabridinua kom tawv nqaij?
Lub sijhawm nws siv rau licorice extract uas muaj glabridin los ua kom pom kev ntawm daim tawv nqaij tuaj yeem sib txawv nyob ntawm ntau yam, suav nrog cov concentration ntawm glabridin hauv cov khoom, qhov zaus ntawm daim ntawv thov, tus neeg ntawm daim tawv nqaij, thiab qhov hnyav ntawm hyperpigmentation. Nov yog qee cov lus qhia dav dav thiab kev txiav txim siab:
1. Lub Sijhawm Ntev Ntev
- Cov txiaj ntsig thawj zaug: Qee cov neeg siv yuav pib pom kev txhim kho thawj zaug ntawm cov tawv nqaij thiab txo qis hauv hyperpigmentation li ntawm 2 mus rau 4 lub lis piam ntawm kev siv zoo ib yam.
- Cov txiaj ntsig tseem ceeb: pom pom ntau dua thiab pom qhov pom ntawm daim tawv nqaij tseem ceeb feem ntau tshwm sim tom qab 8 mus rau 12 lub lis piam ntawm daim ntawv thov tsis tu ncua.
2. Cov yam ntxwv cuam tshuam rau kev ua tau zoo
Concentration ntawm Glabridin
- Kev siab dua: Cov khoom lag luam uas muaj ntau dua ntawm glabridin (piv txwv li, 0.5% mus rau 1%) tuaj yeem tsim cov txiaj ntsig sai dua thiab nthuav tawm.
- Tsawg Concentrations: Cov khoom uas muaj cov concentrations qis dua yuav siv sij hawm ntev dua los qhia pom cov teebmeem.
Kev siv ntau zaus
- Kev Siv Txhua Hnub: Siv cov khoom siv ib zaug lossis ob zaug ib hnub, raws li kev pom zoo, tuaj yeem txhim kho cov txiaj ntsig thiab ua kom cov txiaj ntsig tau sai.
- Kev siv tsis raug: Cov ntawv thov tsis tu ncua tuaj yeem ncua qhov pom kev cuam tshuam thiab txo cov txiaj ntsig tag nrho.
Hom tawv nqaij thiab mob
- Hom tawv nqaij: Cov tib neeg uas muaj cov tawv nqaij sib zog tuaj yeem pom cov txiaj ntsig sai dua piv rau cov neeg uas muaj cov tawv nqaij tawv dua.
- Qhov hnyav ntawm Hyperpigmentation: me me hyperpigmentation yuav teb sai dua rau kev kho mob, thaum mob hnyav dua yuav siv sijhawm ntev dua los qhia kev txhim kho.
3. Cov Kev Kho Hniav Txhuam Hniav
- Kev Tiv Thaiv Hnub Ci: Kev siv tshuaj pleev thaiv hnub txhua hnub yog qhov tseem ceeb thaum siv cov khoom siv tawv nqaij kom tsis txhob muaj pigmentation ntxiv thiab tiv thaiv daim tawv nqaij los ntawm UV puas.
- Moisturization: Ua kom daim tawv nqaij zoo moisturized tuaj yeem txhim kho kev nqus thiab ua haujlwm ntawm cov khoom siv glabridin.
- Exfoliation: Kev tshem tawm tsis tu ncua tuaj yeem pab tshem tawm cov tawv nqaij tuag thiab txhawb kev nkag mus ntawm cov khoom xyaw nquag, uas tuaj yeem ua kom tau txais txiaj ntsig.
4. Kev tshawb fawb soj ntsuam thiab pov thawj
- Kev tshawb fawb soj ntsuam: Qee cov kev tshawb fawb soj ntsuam tau pom tias glabridin tuaj yeem txo qis hyperpigmentation thiab txhim kho cov tawv nqaij tsis pub dhau 8 mus rau 12 lub lis piam ntawm kev siv zoo ib yam.
- Cov ntawv pov thawj ntawm cov neeg siv: Ntau tus neeg siv tau tshaj tawm pom pom kev txhim kho hauv lawv cov tawv nqaij thiab txo qis ntawm qhov tsaus nti hauv ob peb lub lis piam mus rau ob peb lub hlis ntawm daim ntawv thov tsis tu ncua.
Dab tsi yog cov kev mob tshwm sim ntawm covglabridin?
Glabridin muaj ntau yam kev ua si lom neeg thiab cov txiaj ntsig kev noj qab haus huv, tab sis qee zaum, kev siv cov khoom uas muaj glabridin tuaj yeem ua rau qee qhov kev mob tshwm sim. Cov hauv qab no yog cov kev mob tshwm sim thiab kev ceev faj rau glabridin:
1. Cov tawv nqaij ua xua thiab ua xuans
Daim tawv nqaij khaus
- Cov tsos mob: Tej zaum yuav muaj liab, o, khaus, stinging, los yog kub hnyiab.
- Ua rau: Cov tawv nqaij rhiab heev rau glabridin lossis lwm cov khoom xyaw hauv cov khoom yuav ua rau tawv nqaij me.
Kev ua xua
- Cov tsos mob: Tej zaum yuav muaj pob liab liab, erythema, o, lossis khaus hnyav.
- Ua rau: Kev tsis haum rau glabridin lossis lwm cov khoom xyaw hauv cov khoom, uas tuaj yeem ua rau muaj kev fab tshuaj.
2. Photosensitivity
- Ua kom rhiab heev rau tshav ntuj: glabridin tuaj yeem ua rau cov tawv nqaij rhiab heev rau lub hnub ci, ua rau tshav ntuj lossis photosensitivity dermatitis.
- Kev Tiv Thaiv: Thaum siv cov khoom uas muaj glabridin, nws raug nquahu kom siv cov tshuaj pleev thaiv hnub dav dav thiab tsis txhob raug lub hnub ntev.
3. Cov tshuaj hormones
- Muaj peev xwm Hormonal Activity: Thaum glabridin feem ntau yog npaj rau kev siv tshuaj pleev ib ce, qee yam ntawm licorice (xws li glycyrrhizic acid) paub tias muaj cov teebmeem zoo li steroid uas yuav cuam tshuam rau cov tshuaj hormones.
- Kev txiav txim siab: Thaum siv cov khoom uas muaj glabridin nyob rau hauv ntau lub sij hawm ntev, koj yuav tsum tau xyuam xim saib xyuas seb puas muaj cov tsos mob ntawm hormonal tsis txaus.
4. Kev sib cuam tshuam nrog lwm cov khoom siv tawv nqaij
- Muaj peev xwm cuam tshuam: glabridin tuaj yeem cuam tshuam nrog lwm cov khoom xyaw nquag (xws li vitamin C, retinol, thiab lwm yam), cuam tshuam rau nws cov txiaj ntsig lossis ua rau muaj kev pheej hmoo ntawm kev phiv.
- Cov lus pom zoo: Thaum siv cov khoom uas muaj glabridin, nws raug nquahu kom tsis txhob siv lwm cov khoom xyaw uas muaj zog los yog mus ntsib kws kho mob dermatologist ua ntej siv.
5. Tej yam tshwm sim
- Txwv kev nqus:glabridinFeem ntau yog siv rau kev siv sab nraud thiab muaj qhov nqus dej tsawg, yog li cov kev mob tshwm sim tsis tshua muaj tshwm sim.
- Ceev faj: Yog tias koj muaj kev tsis xis nyob lossis qhov tshwm sim txawv txav, koj yuav tsum tsis txhob siv tam sim ntawd thiab nrog koj tus kws kho mob tham.
6. Kev xeeb tub thiab pub niam mis
- Kev txhawj xeeb txog kev nyab xeeb: Tam sim no muaj cov ntaub ntawv txwv txog kev nyab xeeb ntawm glabridin hauv cov poj niam cev xeeb tub thiab pub niam mis.
- Cov lus pom zoo: Cov poj niam cev xeeb tub thiab cov poj niam laus yuav tsum sab laj nrog lawv tus kws kho mob ua ntej siv cov khoom uas muaj glabridin.
Post lub sij hawm: Sep-21-2024
